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pentobarbital will lessen the extent or result of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will lower the level or effect of siponimod by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of siponimod that has a drug tha